General and Systemic Histopathology, C601&C602
    Slide 19: Acute Erosive Esophagitis
    Your slide shows almost a complete cross section of the esophagus.  Note there are several areas of mucosal ulceration and some relatively large, thin walled vessels are present in the lamina propria.

    See this slide with the virtual microscope.

    This is a higher power view of the base of the ulcer. You will see a mixed acute and chronic inflammatory infiltrate in association with the elements of granulation tissue. You should be able to identify both angioblasts and reactive fibroblasts in the base of the ulcer. Remember that even though this is referred to as "acute" esophagitis, there will always be a few lymphocytes involved in the repair process. One practically never sees a pure acute or chronic infiltrate. Also, in this case the injury is one of duration, so some element of a chronic response would be expected. 

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