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General and Systemic Histopathology, C601&C602
     
    Slide 27: Gallbladder with acute and chronic inflammation
     
     
    This section represents only a small slice out of a dilated, inflamed (and no doubt painful) gallbladder.  Undoubtedly there were stones present as well, but we don't have any direct microscopic evidence for them.  Find the mucosa and then work your way through the wall to the serosa.  Pay attention to the inflammatory cells and where you see them.  What about the lamina propria?

    See this slide with the virtual microscope.

    Find the lumen and try to have yourself oriented before looking for the infiltrate. You will see a mixed inflammatory infiltrate consisting of both "acute" and "chronic" inflammatory cells, again lymphocytes are to be expected in the submucosa of a structure associated with the gastrointestinal system. You will see a large amount of granulation tissue on the serosal surface. 


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