General and Systemic Histopathology, C601&C602
    Slide 48: Fibrinous pericarditis
    In this case, we're looking for a thin band of homogeneous, pink staining, proteinaceous material on the epicardial surface of the heart.  This represents an exudate composed largely of protein material.  You will see very few inflammatory cells. 

    See this slide with the virtual microscope.

    Before putting slide on the microscope stage, look at the tissue to find the epicardial surface. This is where you will find the exudate. This exudate is almost totally devoid of inflammatory cells, and consists almost totally of protein (fibrin plus other trash). It looks the way I think "tofu" would look if sectioned and stained. This exudate is a product of renal failure, is completely sterile.  It occurs secondary to the crystallization of nitrogenous wastes on the epicardial and pericardial surfaces.  Renal failure is consequence of many forms of long term kidney disease. 

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