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General and Systemic Histopathology, C601&C602
     
    Slide 29: Hepatic adenoma
     
     
    It's a little tricky to see the area of the adenoma if all you do is slap the slide on the stage of your scope.  See if you can match the areas of the tissue as depicted to the left and then look with your microscope right at the margin of the tumor.  With situations like this, it's really important to see both cell types in one field. 

    See this slide with the virtual microscope.

    Here you can see the cellular differences a little more clearly. The cells that make up this benign tumor do not show much of a lobular arrangement. There are no triads. The individual cells have a "foamier" cytoplasm and somewhat more vesiculated nucleus. I don't think you will find any mitosis. These can become symptomatic by bleeding, and can even cause death by this mechanism. What is associated with these? Hint: think common exogenous hormones women may take. 


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