General
and Systemic Histopathology, C601&C602
Slide 206: Follicular lymphoma
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Hold this slide up to the light and you’ll
have no trouble seeing the nodular aggregations. Even though there is nodularity,
there is still uniform effacement of the expected nodal architecture. That is to
say, the expected microscopic organization of germinal centers, sinusoids and
the like has been completely replaced by the monomorphic growth of the malignant
lymphocytes.
See this slide with the
virtual microscope. |
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Here you can see the nodular, or
follicular-like, arrangement of the malignant lymphocytes. Even though they
superficially look like germinal centers, there is no maturation of cells and
nothing healthy about the organization |
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