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General and Systemic Histopathology, C601&C602
     
    Slide 89: Infant lung with hyaline membrane disease
     
     
    The lung tissue here is quite "meaty," and may not even appear as lung to you.  Fetal lung looks much like this, although in this case there is extensive atelectasis along with the accumulation of the alveolar proteinaceous material.  See how many aspects of pulmonary histology you can identify in this slide.

    See this slide with the virtual microscope.

    A higher power view of one of the hyaline membranes. Note how the histological appearance of infant lung is so much different from that of adult pulmonary tissue. Here you can see how much more cellular and thick walled the alveoli are and how cuboidal the alveolar lining epithelium appears. This cuboidal nature of the epithelium is not a function of the disease, rather reflective of the degree of immaturity of the lung tissue. 


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