General and Systemic Histopathology, C601&C602
    Slide 100: Lung with pulmonary hypertension and embolus
    The changes are subtle in this tissue.  Look at the smaller muscular arteries for the hyperplastic changes.  It might be wise to review normal lung to get an idea of what these vessels should look like before tackling this slide.

    See this slide with the virtual microscope.

    There are actually two things of interest in this slide. First, notice the thickened muscular walls of the smaller arteries and arterioles; changes of pulmonary hypertension. The pulmonary vessels are undergoing hyperplasia to "adapt" to higher than normal pulmonary vascular pressures. This feature contributes to the resistance in the pulmonary vascular bed, and will lead to right-sided heart failure. What are some causes of increased pulmonary vascular pressure ? Also, note the pulmonary emboli. Could these be thrombi? What is the difference? 

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