General and Systemic Histopathology, C601&C602
Slide 64: Lung with squamous metaplasia of bronchial mucosa
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The process of metaplasia
is found intermixed with the typical ciliated columnar epithelium. This
is a reactive or adaptive process and not a true malignancy.
What is the definition of metaplasia? See this slide with the virtual microscope. |
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This picture is of bronchial mucosa, showing the reactive replacement of one type of epithelium for another. It is technically not a neoplastic process, although continued injury of the sort that lead to the metaplasia, can lead to dysplasia and possibly cancer. Here we see respiratory epithelium being replaced by squamous. Smoking was the injury that lead to this alteration. Observe the inflammatory reaction beneath the mucosa. |
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Mark
Braun, MD braunm@indiana.edu
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1998, the Trustees of Indiana University