General
and Systemic Histopathology, C601&C602
Slide 23: Metastatic transitional cell
carcinoma
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Note how "meaty" the
bone marrow space is. Much of the hematopoietic space has been replaced
by scar tissue and tumor.
See this slide with the
virtual microscope. |
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This slide shows metastatic
"transitional cell carcinoma" in the bone marrow. What are the sources
of "transitional cell carcinoma?" First,
try to get oriented by finding some bone spicules and hematopoietic tissue.
The malignant cells occur in clusters and closely resemble malignant squamous
cells. Although these cells don't look too wild, they are not in the right
place. Observe the "desmoplasia" (i.e. fibrosis) associated with the groups
of tumor cells. |
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