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General and Systemic Histopathology, C601&C602
     
    Slide 37: Ovary with Stein-Leventhal Syndrome
     
     
    In this case it's probably easier to see the nature of the problem without the microscope.  The scan at the left shows a markedly thickened capsule and many large and somewhat distorted follicles.  Essentially, no eggs are making it out of this ovary.  What do you think the consequences of the thecal cell hyperplasia are?

    See this slide with the virtual microscope.

    Here you will see a very thickened "capsule" in this ovary.  This capsule in essence "traps" the developing eggs. There is no appreciable inflammation and no cellular atypia. You will see generalized areas of thecal cell hyperplasia. There are small follicles fairly deep in the ovarian stroma. See what you can find out about the physical appearance of women with this disorder. How might the appearance be explained in light of the changes in the ovary? 


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