General
and Systemic Histopathology, C601&C602
Slide 87: Squamous Cell Carcinoma of
Skin
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Here you can see the
malignancy in the center of the skin biopsy. Please take the time
to look at the surrounding skin first. You will see there is rather
significant solar damage to the dermal connective tissue and very likely
there will be dysplasia of the epithelial covering as well.
See this slide with the
virtual microscope. |
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You will see groups and
clusters of malignant squamous epithelial cells extending into the dermis,
and many reveal whirl like clusters of desquamated squamous cells centrally.
Some of these groups have areas of necrosis, and you will see a mixed acute
and chronic inflammatory infiltrate in many areas. |
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