General
and Systemic Histopathology, C601&C602
Slide 118: Lymph Node with Metastatic
Malignant Melanoma
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Although fragmented,
you can see the area of involvement in this lymph node.
See this slide with the
virtual microscope.
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Again the picture pretty
well says it all here. You will see a node partially replaced with groups
of cells that clearly don't belong there. Many contain abundant dark brown
pigment. In general I advise that you look at the subcapsular sinuses and
pericortical sinuses for the first evidence of metastatic involvement.
Of course, in this case, it is no problem to see the altered histology
and the process is considerably advanced. |
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