General and Systemic Histopathology, C601&C602
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Even without the aid
of a stain highlighting collagen or elastic tissue, you can see how markedly
thickened the endocardium has become. This process will obviously lead
to a significant restriction in the dilation and filling of the ventricles. See this slide with the virtual microscope. |
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This is an H&E of an uncommon disease; endocardial fibroelastosis. See how markedly thickened the endocardium is and note the extension of fibrous tissue into the superficial myocardium. Slide #119 shows this with a stain that highlights the collagen. This alteration greatly restricts the ability of the heart to fill and pump effectively. |