General and Systemic Histopathology, C601&C602
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There should be no problem
finding the area of tumor if you simply look at the tissue on a white background.
Note the nodularity of the tumor. Also, there is quite a chronic
inflammatory infiltrate in the surrounding uninvolved renal tissue. See this slide with the virtual microscope. |
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The entire field in this case is composed of the carcinoma. Note how the cells reveal a clear almost empty cytoplasm. These malignant cells contained a lipid droplet at one time, but it was "washed out" during the processing of the tissue. This is one of the most enigmatic tumors we know of. It can metastasize widely, but patients may go for years with it. It often uses the existing vasculature as a framework to grow on. You should see many mitotic figures. |