Cell Biology & Histology A560
    Epithelia and Cell Junctions
     
     

    Epithelium, one of the four primary tissues of the body, is characterized by
    • A free edge or surface and
    • A basal lamina which anchors it to the underlying structure.

    Unlike other tissue types, epithelia consist mostly of cells, with little intervening space between the adjacent cells.

    • The classification of an epithelial layer is based on the shape of cells that comprise it,
      • Particularly the cells on its free or exposed surface, and
    • The number of cellular layers.
    • These structural features also reflect the principal activities of the epithelium.

    Learning Objectives:

    • Understand how epithelia are classified into simple, stratified, and pseudostratified types and the usual functional significance of each type.
    • Recognize the (extracellular) basement membrane of epithelia, apical specializations such as the terminal web, and ultrastructural features of the various types of intercellular junctions.
    • Understand that epithelium forms barriers and compartments by covering and lining the body’s outer and inner surfaces.
    • Understand that epithelium is specialized for protection (or as a barrier), transport, absorption, and secretion.

    Let's start with simple squamous epithelium.

     


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