Cell Biology & Histology A560
    Female Reproductive System, Endometrium
     
     

    Using the diagram in Fig. 19.15, review how the various stages of the uterine (menstrual) cycle correlate in time with the various stages of follicular development in the ovary.

    What hormones directly affect uterine histology and what are their sources?

    Using slides 80, 81, 82, 83 and 84, examine specimens of uterus in different stages of the menstrual cycle (Fig. 22-17). These slides do not show distinct differences between early and late in either the proliferative or the secretory phases, as in Junqueira’s figures, but at each stage you identify, note the thickness of the endometrium (the basal and functional layers are also more easily distinguished here); the presence or absence of mitotic figures, the appearance of the glands and secretory cells, and the nature of the surface epithelium and the vascular supply. On each slide, endometrium is at one "end" of the section with deeper layers at the other "end". Note that some specimens are not uniformly well-stained.

    Proliferative phase

    Slide 80, 83 Fig. 22-17a,d

    Secretory phase

    Slide 82, 84 Fig. 22-17b,e

    Onset of menstruation

    Slide 81 Fig. 22-17c,f

    During the cycle, what changes occur in the endometrial glands and in the various tissue layers, and what is the significance of these changes?

    Why is it important that the basal layer of the endometrium is not involved in menstruation?

    How is the endometrial lining re-established after menstruation?

    Now for the cervix and vagina.