Cell Biology & Histology A560
    Cartilage and Bone
     
     

    Cartilage is a specialized, semi-rigid connective/supporting tissue characterized mainly by
    • The predominance of ground substance in the extracellular matrix.
    • The ground substance contains varying amounts of collagen and elastic fibers, giving rise to three broad categories or types of cartilage.

    Hyaline cartilage, the most common type, contains the smallest proportion of fibrous material in its ground substance. Examine the cartilage in the trachea and the larynx (slides 2, 7 and Figs. 7-1 and 7-2).

    • Identify perichondrium,
    • Chondroblasts,
    • Chondrocytes,
    • Lacunae

    What causes the chondrocytes to frequently be clustered?

    The perichondrium is an example of what tissue type studied previously?

    Clinical note:  The avascularity of cartilage limits its size according to the distance small molecules can diffuse through the matrix to nourish the chondrocytes. The matrix is a barrier to the entry of large proteins like immunoglobulins and also to lymphocytes, which is important for the practice of reconstructive and cosmetic surgery since cartilage can be transplanted from one individual to another without rejection by the immune system.

    Fibrocartilage and elastic cartilage is next.