Introduction
  Prerequisites
  Course Syllabus
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 Mark W. Braun, MD
 braunm@indiana.edu

 
   Mechanisms of Human Disease 
    The Plight of Native Americans and European Conquest
 

 
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The mission of this course is to give the student a detailed look at the important infectious diseases that were so devastating to Native Americans following European and African contact.

We will begin by considering the arrival of the First Americans. Their founder population size, degree of genetic homogeneity and what in the way of microbial 'baggage' they might have brought with them.

We will then explore the emergence of 'herd' type infectious disease in human populations and how the Americas differed from Europe.

The majority of our time will be spent studying selected infectious disease that so substantially reduced the numbers of Native Americans  

 

Native American Winter Count, 1701-1727
during the period of conquest and colonization. We will consider the biological effects, epidemiology, cultural and social consequences of disease such as: smallpox, measles, influenza, malaria, yellow fever, typhus, tuberculosis and syphilis.

Some of the reading for this course will be provided online. If you plan to do some of the work from home, there some basic computer requirements.

 
 
 Indiana University School of Medicine, copyright 2004