| Symptoms
& History
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Findings
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and X-Ray
Differential
Diagnosis
The
Disease
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Quiz
& Evaluation
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Major Immune System Abnormalities
in AIDS
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Lymphopenia
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Primarily due to loss of CD4+
helper/inducer cells.
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One observes an inversion of
the CD4:CD8 ratio
Decreased T-Cell Function
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Loss of memory cells
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Decrease response to mitogens
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Decreased cytotoxicity
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Decreased interferon production
Altered B-Cell Function
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Hypergammaglobulinemia with
circulating immune complexes.
- Often shows up as an elevated protein
on chemistry profile tests.
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Poor antibody response to new
antigenic stimulation.
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