Symptoms
& History
Physical
Findings
Stop
& Think
Lab
and X-Ray
Differential
Diagnosis
The
Disease
Treatment
Conclusions
Quiz
& Evaluation
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Major Immune System Abnormalities
in AIDS
(Continued)
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Altered monocyte and
macrophage function
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Decreased chemotaxis and phagocytosis.
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Diminished HLA class II expression.
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Decreased capacity to present
processed antigen to T-cells.
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Increased spontaneous secretion
of tumor necrosis factor and certain classes of interferons.
Consequences of altered T-cell
function
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Susceptibility to opportunistic
infections
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Increased incidence of neoplasms
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Decreased delayed (Type IV )
hypersensitivity
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