General
and Systemic Histopathology, C601&C602
Slide 49: Bone Marrow Hyperplasia
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Normally one sees about
50% fat and 50% hematopoietic bone marrow. It's obvious just by looking
at the scan to the left that this bone marrow is at least 80-90% cellular.
That's definitely hyperplastic.
See this slide with the
virtual microscope. |
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The changes here may
seem subtle, and it would be wise to look at normal bone marrow first,
but this slide does show generalized hyperplasia of all hematopoietic elements.
The key to seeing this is knowing how much bone marrow fat there normally
is. Generally fat represents about 50% of the marrow space, at least in
bones that are normally involved in hematopoiesis. The fat cells are generally
distributed evenly throughout the marrow tissue. See if you can identify
the expected red and white cell precursors. |
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