General and Systemic Histopathology, C601&C602
    Slide 7: Healing fracture of bone.
    This slide is obviously has two sections of tissue. Both are of a rib and the lower portion shows a partially healed fracture line.  You can see the developing callous one one side and there is abundant granulation tissue in the fracture line itself.  We split the fracture line open at the time the specimen was embedded so as to highlight where to look for the healing process.  In life, the fracture was closed and the edges were knit together with the newly formed granulation tissue.

    See this slide with the virtual microscope.

    This healing "fracture" is a approximately two weeks old, and shows early changes of the healing process. Note the remodeling taking place by the osteoclasts and the rather marked degree of fibrosis (scarring) that is taking place as the new bone is being formed. In your slide, you should be able to see many active fibroblasts and angioblasts as part of the initial healing "team." See if you can find the area just by looking at your slide. 

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