General
and Systemic Histopathology, C601&C602
Slide 41: Liver with acute and chronic cholangitis
and fibrosis
|
Here you can see the
beginnings of cirrhosis. There is scarring, necrosis and a nodular pattern
of regeneration.
See this slide with the
virtual microscope.
|
|
Here the big changes
are in the triads. This is a good example of the disruption of the normal
architecture of the margins of the triads. Note the loss of definition of
the "limiting plate" of the triads (the first layer of hepatocytes nestled
right up to the triad is what is referred to as the limiting plate) with the
marked degree of inflammation. There is early "bridging fibrosis" between
the triads. This fibrosis represents the beginnings of cirrhosis. What are
some of the causes of this condition? |
Back to Home
|