Physical Findings

Stop & Think

Lab and X-Ray

Differential Diagnosis

The Disease

Treatment

Conclusions

Quiz & Evaluation

• Most present with painless enlargement of a lymph node.
• Constitutional symptoms may or may not be present.
• The "A" designation indicates the absence of symptoms.
• The "B" designation indicates the presence of symptoms. Examples
1. Weight loss (10% of body weight)
2. Fever
3. Night sweats
• Biopsy is required for diagnosis and classification
• Nodular sclerosing
• Mixed cellularity
• Lymphocyte predominance
• Lymphocyte depletion
• Staging is required to evaluate extent of spread and therapy.
• Abdominal and chest CT
• Laparotomy if indicated by CT (liver and lymph node biopsies, possibly splenectomy).
• Bilateral iliac crest bone marrow aspirates with biopsy.