Clinical Case: Mrs. Richardson's Blindness
 
Symptoms & History

Physical Findings

Stop & Think

Lab and X-Ray

Differential Diagnosis

The Disease

Treatment

Conclusions

Quiz & Evaluation

Plaques of multiple sclerosis.
  • Found throughout the white matter, variable sizes.
  • Commonly occur around the lateral ventricles.
  • Seem to follow the paraventricular veins.
  • Frequent in the optic nerves and area optic chiasm.
  • Seen in the cerebellum, brainstem and spinal cord.
  
  
Active plaques:
  • Myelin breakdown.
  • Macrophages 
  • PAS+ debris
  • Roll cursor

Active plaque

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