Introduction
Very Sociable
Guy
Chest Pain
Girl with a Rash
England 1944
Trouble Healing
Morning Stiffness
Bruises Easily
Shortness of
Breath
Drug Interactions
Review
Thanks to
Quiz
Please |
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Is there something
that affects clotting with a normal PT and aPTT?
- Protein C deficiency
- Protein S deficiency
- Anti-thrombin III
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- Elevated homocysteine
- Mr. JH's value is 28 micromol/L
- Desirable value = <13 micromol/L
Inborn errors of homocysteine metabolism |
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Enzyme |
Cofactor |
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Cystathionine
synthetase |
Vitamin B6 |
Methionine
synthetase |
Vitamin B12 |
Methylenetetrahydrofolate reductase |
Folate |
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- Elevated levels also seen with low dietary
intake of folate, vitamins B6 and B12.
Are you kidding? An MI on the basis of
high homocysteine?
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