Introduction
Very Sociable
Guy
Chest Pain
Girl with a Rash
England 1944
Trouble Healing
Morning Stiffness
Bruises Easily
Shortness of
Breath
Drug Interactions
Review
Thanks to
Quiz
Please |
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Let's check for
factor V Leiden first.
- This is by far the most common protein
abnormality leading to thrombosis.
- It occurs in approximately 5% of the
Caucasian population.
- The DNA sequence for both wild-type and
Leiden factor is known.
- DNA probe of Mr. CV's genome reveals he
has the Leiden variant of factor V.
Once activated, V Leiden cannot be degraded by
protein C. It's a runaway train.
Condition |
Incr. risk |
Heterozygosity |
7X |
Heterozygosity + birth
control pills |
35X |
Homozygosity |
80X |
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Five percent of the population,
is this for real?
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