About 60% of genetically determined hypercoagulable states are explained by the following:
- Factor V Leiden
- Prothrombin polymorphism
- Mutations of Protein C, S and antithrombin III
| Prevalence of Genetic Conditions | |||
| Factor | Prev in % | ||
| Factor V Leiden (Caucasians) | 5 |
 |
|
| Factor V Leiden (US Hispanic) | 2 | ||
| Factor V Leiden (US African) | 1 | ||
| Factor V Leiden (Native American) | 1 | ||
| Factor V Leiden (Asian American) | 0.5 | ||
| Prothrombin Polymorphism | 2-3 | ||
| Protein C deficiency | 0.5 | ||
| Protein S deficiency | 0.7 | ||
| Antithrombin III deficiency | 0.17 | ||
I would have never guessed these were this
common. What can we do for them?
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