Coagulation Disorders Tutorial
 
Introduction

Very Sociable Guy

Chest Pain

Girl with a Rash  

England 1944

Trouble Healing

Morning Stiffness

Bruises Easily

Shortness of Breath

Drug Interactions

Review

Thanks to

Quiz Please

 More confirmatory tests for thrombotic disorders.
 
  • Homoscyteine levels: High levels cause both venous and arterial thrombosis.
    • Works by diminshing activity of proteins C and S, therefore the routine labs (PT and aPTT) will be normal.
    • Folic acid in large quantities will drop homocysteine to safe levels.
  • Anti-Cardiolipin antibody levels: Also known as lupus anticoagulant, this antibody causes a prolonged aPTT in the lab, but paradoxically causes hypercoagulation in the patient.
  • Lower frequency problems: genetically abnormal clotting factors or plasminogen.

Holy cow! Show me a diagram of this stuff, maybe that'll put it in perspective.

A few cases ought to help me understand this.                                               Back 

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