Measuring WBCs

• The Basics
• Reactive
• Terms

• Acute Leukemia
• Dysplasia
• Myeloproliferative

• Acute
• Chronic 

Quiz Please

• Are a heterogeneous group of neoplasms that originate in a precursor cell that normally completes maturation to a "terminally" differentiated cell of the myeloid series (RBC, WBC, monocyte or platelet).
• The three basic conditions are:
• Acute myelogenous leukemia, characterized by clonal proliferation of an immature myeloid precursor cell.
• Myelodysplastic syndromes, characterized by ineffective erythropoiesis and a variety of cytopenias.
• Chronic myeloproliferative disorders (neoplasia), of which chronic myelogenous leukemia is one. 
• Chronic myeloproliferative disorders are characterized by increased production of "terminally" differentiated myeloid cells (RBCs, WBCs, platelets, etc.).
• These are disease of the "stem cell," the basic progenitor cell of the bone marrow. 
• When the stem cell is sick, everything that flows from it is sick too.