• Quinine and melfoquin.
• She also received 3 units of blood for her anemia (eventually).
• She was sent home feeling better and with a HgB of 7.8.
• Unfortunately she was brought back three months later in a coma.
• She died on the second hospital day with cerebral malaria.

• RBCs infected with P. falciparium develop little 'knobs' on the membrane surface.
• These knobs bind to ICAM-1 receptors on the capillary and venule endothelial cells.
• This is the disaster of cerebral malaria.
  • Not growth of the bug in the brain.
  • Rather, small vessel occlusion.
  • The picture to the right shows this.

Click for more interesting facts about malaria.