General and Systemic Histopathology, C601&C602
Diseases of the Nervous System
In this unit we will
be studying disorders of the central and peripheral nervous systems. The one
over riding feature of pathology of the nervous system, especially so for
the brain, is the location of the lesion. Time and again we will see that
a perfectly benign tumor or seemingly minor and seemingly inconsequential
injury can be devastating, if not lethal, when it occurs in a strategic
location. Just as it is said of real estate, the three most important facets
of a property are its location, its location and finally its location. The
feature distinguishing central nervous system from other systems we have
studied is the fact that the brain is a veritable prisoner within the fixed
cranial vault. Edema of the brain and mass lesions have no where to go.
The pressure on surrounding structures will prove most important. Still,
as with every other organ the nervous system suffer injury from all the major
categories of illness we have repeatedly visited.