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Introduction
Case1:
Vomiting
Case 2:
Cough & fever
Case 3: Bruising
Case 4: Sore
throat
Case 5: Jaundice
Case 6: Flu & fever
Case 7: Diarrhea
Case 8: Black
Robe
Case 9: Back Pain Catching the
beast
Thanks to
Quiz
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We know it's TB
because we were able to identify the bug.
- No, it wasn't possible to culture the
organism.
- But it was possible to identify its DNA,
even after hundreds of years in the soil.
- A small amount of bone was pulverized and
DNA extracted.
- Native American DNA was grown, confirming
the authenticity of the extract.
- Then primers specific for diagnostic
regions of M. tuberculosis were used.
- The sequenced DNA was a perfect match.
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- To the right is the match of a 92 base
pair fragment of ancient DNA extracted from the Anuhuak's bones.
- It matches perfectly the sequence for the
IS6110 genomic region of M. tb.
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What do you know, a specimen hundreds of years
old confirming an infection.
One more to go, and it's
pretty gory so hang on.
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