Leukemia Review
 
Introduction

 Measuring WBCs

  Myeloid Leukemias  Lymphoid Leukemias Sources of Error

Quiz Please

In summary...........
  • Leukemias are malignancies of either myeloid or lymphoid origin in which there is substantial bone marrow replacement.
  • Malignant cells are often present in the circulating blood.
  • Symptoms are generally due to suppression of the healthy marrow.
    • Anemia
    • Infections
    • Bleeding
  • Acute leukemias arise from one cell in a committed cell line, and are characterized by proliferation of immature cells (blasts).
    • Untreated acute leukemias have a rapid course.
    • Acute leukemias tend occur in a younger age group.
  • Chronic leukemias are characterized by proliferation of mature cells.
  • Chronic leukemias tend to occur in an older age group.
    • Chronic myelogenous leukemia is one type of stem cell malignancy.
    • In addition to CML, there are myeloproliferative disorders.
  • Malignancies of lymphoid origin may occur as either a leukemia, with significant bone marrow involvement, or as a lymphoma.


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