Leukemia Review
 
Introduction

 Measuring WBCs

  Myeloid Leukemias  Lymphoid Leukemias Sources of Error

Quiz Please

 The accelerated phase, and blast crisis of CML
  • After about 3 years, about 50% of patients enter an accelerated phase.
  • Generalized marrow failure with increased percentage of blasts.
  • Increased numbers of basophils in the peripheral smear.
  • The blast crisis, essentially conversion to an acute leukemia, typically comes about 6 months after the beginning of the accelerated phase.
CML blast crisis
  • Peripheral blood of someone in blast crisis. Note increased numbers of blasts and basophils. (Roll cursor over image to highlight them.)
What happens to the other 50% of patients with CML?                   Back

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