The lung is subject to injury in a number of ways including what may be termed "innocent bystander" conditions. In this laboratory, we will be looking at the full gamut of diseases, ranging from hyaline membrane disease of the newborn to metastatic carcinoma in the elderly. As will become evident, conditions that alter the oxygen exchange membrane's capacity to function will have almost immediate consequences. In this regard, you will want to understand the mechanism of pulmonary involvement in congestive heart failure, pulmonary embolization (think of all the various things that can embolize) and primary inflammatory conditions of the lung.

Contrary to the public posturing of the tobacco industry, smoking leads to increased incidences of practically every pulmonary disorder. One of the most common smoking related pulmonary diseases is emphysema, a condition in which pulmonary tissue is lost for good. To understand the process of emphysema you will need to know the difference between obstructive and restrictive conditions affecting of the lung. Practically everyone knows of the association of smoking and lung cancer, but what histological type of  cancer is most common among smokers? These and other fascinating issues will be addressed in the pages that follow. Read on.
 

Slide 1, Cryptococcal pneumonia.	Slide 1, Cryptococcal pneumonia.	Slide 36, pneumoconiosis of lung.	Slide 58, lung with abscess.
Slide 64, lung with squamous metaplasia of bronchial mucosa.	Slide 68, lung with bone marrow embolus.	Slide 70, lung with bronchiectasis.	Slide 72, lung with healed pleuritis.
Slide 74, lung with acute passive congestion.	Slide 76, lung with tuberculosis.	Slide 76, lung with tuberculosis.	Slide 80, lung with metastatic renal cell carcinoma.
Slide 80, lung with metastatic renal cell carcinoma.	Slide 89, infant lung with hyaline membrane disease.	Slide 89, infant lung with hyaline membrane disease.	Slide 100, lung with pulmonary hypertension.
Slide 101, squamous cell carcinoma of the lung.	Slide 101, squamous cell carcinoma of lung.	Slide 107, lung with atherosclerosis.	Slide 108, lung with pulmonary embolus.
Slide 120, lung with lobar pneumonia	Slide 135, lung with disseminated intravascular coagulation.	Slide 172, Interstitial pneumonia	Slide 201, emphysema and pulmonary edema
			I'd like to take the quiz now.
Slide 211, alveolar cell carcinoma of lung	Normal Lung	Dr. Whoopie explains emphysema

Mark Braun, MD braunm@indiana.edu
Copyright 1998, the Trustees of Indiana University